Conjunctival Nevus: Symptoms, Causes and Treatment Labial melanotic macule Melanotic macule. Benign. Dark spot on labia (or lip). Analogous to lentigo simplex. Hyperpigmented basal keratinocytes & dermal melanophages. Slight in single basal melanocytes; NO nests. More info like this in What Is Melanonychia? What Causes It and How It's Treated
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